Keratinocyte Growth Factor human, KGF, recombinant, expressed in E. coli, powder, suitable for cell culture

Code: K1757-10UG D2-231

Analysis Note

The proliferative activity is tested in culture using the murine hematopoietic cell line BaF3.

Application

Keratinocyte Growth Fact...


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€426.00 10UG
€523.98 inc. VAT

Analysis Note

The proliferative activity is tested in culture using the murine hematopoietic cell line BaF3.

Application

Keratinocyte Growth Factor human has been used:as a component of epithelial growth mediumas a positive control for antigen to determine the activity of the antibodyto analyze the influence of KGF associated with thermo-sterilized carboxymethyl chitosan (NOCCts) in the reduction of pericardial adhesions

Biochem/physiol Actions

Keratinocyte Growth Factor(KGF) stimulates proliferation and differentiation of keratinocytes and other cells in the epithelium. It induces chemotaxis of microvascular endothelial cells and neovascularization of rat cornea. It stimulates the hyaluronic acid synthesis in proliferating and migrating basal cells. KGF contributes to the survival of cells under stress conditions. KGF is highly expressed in injured and inflamed epithelial cells, thereby, promotes wound healing.

General description

Keratinocyte Growth Factor(KGF) is a 18.9 kDa growth factor, spanning 163 amino acids, belongs to the fibroblast growth factor family. It includes a secretory signal sequence and shares 39% identity with FGF-Basic. It is expressed in a number of stromal fibroblast cell lines, mesenchymal cells but absent from normal glial cells and epithelial cell lines.

Physical form

Lyophilized from a 0.2 µm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.

assay≥95% (SDS-PAGE and HPLC)
biological sourcehuman
formpowder
Gene Informationhuman ... FGF7(2252)
impurities1 EU/µg
mol wt18.9 kDa
packagingpkg of 10 and 50 µg
potency1.0-10 ng/mL ED50/EC50
Quality Level200
qualityendotoxin tested
recombinantexpressed in E. coli
storage temp.−20°C
technique(s)cell culture | mammalian: suitable
UniProt accession no.P21781
Cas Number148348-15-6
Pack10UG
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